Which is exactly what's so compelling with regard to ClojureScript and say Om or any one of the React wrappers out there: you guys already use Clojure and ClojureScript and its libraries are incredibly pragmatic and designed for "real work". CoffeeScript would seem more like language play than ClojureScript, but of course I'm speaking as an outsider. :)
Also if you haven't already, take a look at David Nolen's recent talk on Om Next[1]. Personally if I were using Clojure on the backend, I'd be pushing hard for it on the frontend too.