There are
a lot of people on HN, and
a lot of people with downvote privilege, and there are
a lot of people who just generally downvote because they disagree with something.
Even if your opinion is completely positive, if people disagree, and a lot of people see it, you will get downvoted just because they disagree (and no one will reply to your comment to disagree, it's a drive-by-downvote).
There's also verification of this by HN mods: Several comment threads exist where they keep increasing the downvote threshold (from 300, to 400, to 500, and beyond). But it still doesn't solve the problem.