No they aren't. Transgenic mouse models are a $billion industry. We do not understand biological mechanisms nearly enough to not use live animal models. We are not even able to recreate single cell organisms with our level of knowledge and engineering.
>>FYI: making a new mouse models requires lots of chopping off heads of mice whom don't possess the desired gene. While transgenic, highly-edited living models might be nice, there's probably a more humane and simpler way to do the exact same thing.
Ah, the real root of your argument. Do you even know what the word humane means? I work in a labroatory and the animals are treated better than the people. Yes, a lot of mice are killed.. but for a reason. You say there's probably a simpler way to do the exact same thing, but there simply isn't. I wish more people were actually educated in this matter, but emotional responses tend to get more results.