and/or ad-proxies that run off the same domain, more integrated and less "blockable" ads (like sponsored stories and in-content ad reads), complicated and bloated JS ad-blocker-blockers (or ad-blocker-detectors), even more complicated ad-blocking code (which can already have a pretty significant performance impact on some sites), and more.
It's a race to the bottom now boys, and the most invasive ad companies are going to win!