If it was purely based on luck, without any talent involved, you'd expect billion dollar companies to be more evenly distributed, and not cluster among certain individuals.
This factor alone accounts for a large percentage of repeat successes. Square probably never would have obtained the capital necessary to become competitive, had it not been for Twitter.
But honestly, for all their funding, even most of these second tries turn out to be failures. What you're really doing here is confusing selection bias with skill: take a pool of enough entrepreneurs, and eventually, just by chance, you'll find someone who has repeat successes.
There's only 170 companies on this list: https://www.cbinsights.com/research-unicorn-companies
The fact that there's even more than one company on it that has a repeat founder suggests that there's something more than selection bias going on her, given the sheer amount of startups started every year.
So the next thing we could do is take a look at if there's other correlations to these repeat founders besides their ability to get capital. I would argue that the fact that most of them are intelligent at least merits a look as a FACTOR that might help them.
I agree with you that talent is a thing. That said, the Matthew effect is also a thing. Winning tends to compound – partially because talented people are repeatedly successful, but even lucky untalented people can be repeatedly successful because of all the attention they get.
The example that's coming to my mind now is a little silly but – there are lots of funny people on Twitter who barely get any retweets, and there are moderately funny things said by popular people on Twitter who get tonnes of retweets and responses suggesting that they're the funniest people ever.
It takes a lot of work and/or luck (probably usually both) to get to the point where people just lap up everything you say, but once you're there, there IS a certain Halo effect of sorts.
Sorry if not water-tight, just rambling here
In the long run, luck and genius are probably both necessary but not sufficient; I have no doubt that Zuckerberg's a very smart guy, I just think there are many, many people just as smart who aren't billionaires.