I disagree. Directly, yes, the average user doesn't care. But
application developers care; peer-to-peer protocols become a lot trickier with IPv4 due to the pervasive deployment of NAT; two machines ostensibly on the Internet can't connect to each other, requiring instead the use of STUN servers, which then requires infrastructure somewhere, or just doing it client-server, or some mix like having "supernodes" (like Skype, prior to MS tearing it out) that route traffic for NAT'd devices.
The ability to actually connect arbitrary devices, I hope, will be something that people will take advantage of. I know for many game servers I set up with siblings, the ability to not need to mess with a router's crappy "port forwarding" would be a welcome change. (Even if I had to mess w/ some local firewall, but that can perhaps be much more tightly integrated or at least, a better UX.)