Well, if you have to refuel every eight minutes, then the time to fill up becomes quite relevant. Not to mention that the main problem will be tyres, as those likely won't do a whole lot of miles at such speeds. Qoute: "In testing Michelin had run the Veyron’s massive meats on its tire dyno at 270 mph — the fastest it can spin — for 20 seconds, then at 250 mph for 20 seconds. It repeated that cycle two more times. Then the tires exploded." http://www.motortrend.com/news/bugatti-veyron-grand-sport-vi...
The tires also cost tens of thousands of dollars. The wheels need to be replaced fairly frequently as well, and they also cost tens of thousands of dollars. Supposedly there are Veyron owners who ship their car to a destination and then follow along in their private jet because that's cheaper than driving the car there. The P100D isn't cheap, but the Veyron is a whole different category of expensive.
There's a lot of cars that are like that. Cost in Fuel, Miles and general depreciation. Just ship it. Its not that crazy.
Also if anyone wants to see someone do a full on heavy run of the Veyron check out Ben on Goldrush 2015? He ran his I think to 255mph if memory serves me right...