This to me is the crux of the matter. If you attempt to hand wave away national sovereignty via globalism or even as pdog says regional globalization, you effectively are advocating traitorous policy (unless specifically called for via constitutional means of alteration of the constitution), not only that, but if the US was to embrace that method, it would lose legitimacy as a government. I don't buy for a second this hullaballo about inevitable globalism. Yes, we have global markets that all effect each other, that's not disputable, what is disputable is that we should allow that excuse to further undermine basic principles of national sovereignty, or further, to undermine the national sovereignty of other countries via imperialism wrapped in banners of globalism.
https://youtu.be/RgcdRCWEt4Q?t=5097
Keep in mind that's a Larouche video, so retain a skeptical view.
For example, TPP was seen coming down the line, but the powers that be recognized this, which is why they twisted the arm of congress into passing fast-track, in which congress, potentially unconstitutionally, traded powers of treaty review in exchange for ~100 optional objectives from potus. This was legal maneuvering to prevent just such objections when they are going to try to shove TPP and similar nafta 2.0 things down our throats. The other thing they have been doing is calling things trade agreements which are really treaties, but trade agreements fall under different rules.
I would also say that the passage of fast-track is in violation of the nondelgation doctrine, but that's just a principle not a law.
Thesis: Globalism
Antithesis: Nationalism
Synthesis: Regional Globalization