Encryption currently works on Riot Web, iOS and Android, certain bugs excluded - but it's missing a lot of UX work. (Among other things, you have to manually verify each and every device the people you talk to use, there's no way for them to say "these are all my devices, if you trust me, you trust them" yet. You also lose chat history at present if you switch devices or log out.) If you're able to work around the UX, the underlying protocol is fine and has been audited, with certain tradeoffs discussed in the report.