That is one area where Salesforce shines. APEX and Visualforce can get you just about anything you may need for customizations. I'm sure something similar will pop up, but then people will complain about having to sell your soul to them, too :)
Workato is another nice tool to augment Quickbase & Airtable. It's like Zapier, but allows you to add some code (Ruby in fact) to do custom hooks.
I guess it really depends on how complex you need to go, which then brings me to my point about being master-of-none - at that point you're losing your abstraction and essentially building a custom app.