When you account for the full lifecycle of fossil fuels, from the extraction, refining, transportation, and ultimate consumption and measure that impact in both short-term impact (coal-mining deaths) vs. long-term impact (climate change, pollution, cancer) you'd find that nuclear is the best option.
I'd risk a %0.00001 chance of dying by cancer sooner living next to a nuclear plant vs. a 1.0% chance of dying in a road collision with a fuel tanker or a 0.05% chance of dying sooner with emphysema by living close to a coal-fired plant. (I made those numbers up by the way; but my order of magnitude is spot-on)
As a person who worked in this industry, understands the economics of it, and has compared the costs of coal/wind/gas/nuclear, I can confidently say that nuclear can be safe and affordable as an energy source if we are committed to safe and conscientious use of it.
(BTW, for a month, I slept next to a nuclear reactor that was approximately 500 feet away from my bunk. My total radiation dose for that trip was less than I'd get in the same time hanging out at Grand Central Terminal (a location that would it to be certified as a functioning nuclear reactor would be out of specification as emitting too great a dose of radiation to those who work there)
http://www.pbs.org/wgbh/pages/frontline/shows/reaction/inter...