I think people also forget that it's not as simple as taking a pill and all is good. All medications carry side effects and risks. Even Tylenol can cause major problems like hearing loss down the line. As I recall, the life expectancy of this cohort is close but still below the general population. This difference is probably a reflection of a lower quality of life, which don't ultimately take their toll for a long time. There's also the ongoing risk that the drugs may fail to work at some point or that the patients may not be a good candidate for them or there may be interactions interfering with other treatments.