Kalydeco is truely a miraculous drug. My niece takes it and it has changed her life. It changed her appetite and allowed her to put on weight, and now looks much healthier. I will admit I was hoping that it would make the effects of CF more hidden (she still has to take other drugs, do physio and watch out for chest infection risks), I am still thankful that the Australian government subsidizes it for her down to $6.40 per month instead of the cost of a family car per month (which is obviously unaffordable to her parents).