> Scheme does not have that for instance, SFRI-10 reader macros need to be wrapped in `#,()`, you can't just dump JSX or XML in Scheme source and expect it to work.

That's not 100% true.

See SRFI-105 which gives you infix expressions without needing to wrap them, and mixing and matching is supported the moment you dive into reader macros.

    #!curly-infix
    (+ 2 {a + b + c})

You do need to enable the reader modification, either in your own read (useful if you want safe eval, and parsing in limited environments), in which case you'd just provide an argument to read, or if you want it globally it'll probably just look like:

    #!jsx
    DOM.render(
      <h1>Hello world</h1>,
      document.getElementById((string-append "hel" "lo"))
    )

Writing the reader would be considerable work, but hardly impossible for Scheme to play nicely.