Major things that are interesting just from the abstract: 1) their targeting dna aptamer binds to nucleolin (how this isn't binding to the nucleolin in normal cells is beyond my knowledge, but my guess is that the protein is expressed somewhere other than the nucleolus of the tumor cell). 2) Doesn't seem to affect mice without tumors, so a good thing?
There's nothing else I can think of that compares. Being a "technical person", I struggle with some embarrassment talking to them. The "seriously...this is best science can do???" overtones are there.
Additionally, this is a similar idea to chemo embolization procedures (something I know is done in the US for some liver metastasis, but is being investigated for other solid tumors), where a catheter delivers a massive dose of chemotherapy at an artery supplying the tumor, and then closes that artery off.