> Jews for example more likely to have Tay Sachs disease.
Sure but it's not because they practice Judaism. And since one can convert to judaism, I've never heard about someone who can convert his genes to "jew genes".
> Sickle cell disease affects blacks disproportionately.
Sure but it isn't necessary because their skin are dark, when you can find people from Sri Lanka or India who have a skin blacker than African people yet they don't have this disease prevalence.
See what you are doing here? you are mixing up genetics which can be used to establish statistical facts about gene expressions, and semantics AKA social construct. And this sort of sophism can easily be exploited to make broad generalizations about the behavior of arbitrary racial groups you've established under pretense of science. That's why the notion of race for humans is completely absurd.
What race are people living in Madagascar? most of them aren't negro looking, what race the Yemeni? the afghans? they don't look like Arabs...