...because then it's not autoplay anymore?
Notably though: If some dialog like this came up even on a specific site like Youtube where I would almost invariably benefit from granting those permissions, I think there is a huge percentage chance I would knee-jerk deny the permission even when if I stopped to think about it, denying that permission would probably make my user experience worse. Lastly, there is an almost infinitesimal chance of me ever seeking out the settings to re-evaluate my choice on this.
Still, if I've managed to allow notifications to slack/discord I'm sure I could figure out allowing autoplay on YouTube/twitch.