Let's be generous and say the WhatsApp was a 10x unicorn so FB overpayed only 9B for it. Which makes 4.5B loss per false negative on each founder. If a false positive was, on average, 1M loss (which is an extremely generous in an organization such as FB in my recollection), it means you could have had 4000 false positives for each of these negatives and still come ahead.

And, it brings us back to the Type I and II errors - it's always cheaper to make one, which has a limited downside than the unknown (potentially very high one). Typical example given is that while you are on the way to an expensive cruise you realize that you might have forgotten to turn off the stove. If you go back you might miss your 10K cruise. If you cary on, you might lose you 1M house. On average, people who miss cruise in such circumstances fare much better than ones, who risk their houses.