Corporate will not configure anything unless it costs them millions. Same for Mobile (which breaks frequently but thank you very much) and same for wireless networks.
Nobody will update their machines that haven't been updated since the 90s because your protocol needs a new port to be freely accessible. Nobody will thusly adopt it and in turns nobody will update their machines.
The TCP/UDP/ICMP trio has been ossified as the ground protocols of the internet, ports 53/80/443 for traffic and TLSv1.2 for SSL traffic. Almost everything outside these parameters breaks in a variety of networks from "bad performance" to "simply doesn't work", depending on whether you sit on a VPS or a normal landline like business or consumer DSL.
We have to deal with that if we want updated protocols to even remotely have a chance of adoption. As I have repeatedly said, this is the reality of the modern internet, face it or have you protocol forgotten and unused.