It's amazing how many "conservatives" I've run into who've never been to San Francisco, but somehow "know" that it's a liberal hellhole that everyone hates.
I think Republicans hate all blue States. Due to America's peculiar Electoral College system one man is not one vote. This keeps California severely disenfranchised in American politics.
Californians are second class citizens. And when they try to exercise their state rights the Republicans are quick to stop them.