Sure, but now you need C code that needs to be aware of your trampoline, specifically. Good luck if it's an existing library. Also, what happens if there are multiple interleaved C parts of the stack, and the innermost one invokes the trampoline? What happens to the ones in the middle? It all sounds awfully like setjmp/longjmp (which is the one thing that you never do in C if you want to interoperate with anything in a sane fashion).

And I don't think FFI direction matters much. The moment you have callbacks, your stack has interleaving of languages anyway (i.e. X called into Y which called back into X). Does it really matter which language the innermost and the outermost stack frames belong to? You still need to handle the mix in the middle.