Don't use grid, the main thing I'm working on has hand-made CSS (with a mobile first layout (with some sizing for larger display)
https://doplaces.comOn another I'm just getting into - working on a simple one/two column thing (large screen two block columns, small screen goes to one some text/image scaling).
I find a lot of CSS frameworks are over-engineered, and with addition of various modules and tools adding redundancy to a site's CSS soup.
I can see a lot of refinement can be made by paring out CSS parts into several sub-classes and then mix them together in the element class assignment (I cant say all my stuff is like that yet, but that what I'm striving for.) I'm just getting into front-end so I'm learning as I go.