That's the official answer. The more nuanced and correct answer is that DOS (16-bit realmode) apps won't work due to the hardware lacking the functionality --- blame AMD, not Microsoft, for that --- but there's no such limitation for Win16 (16-bit protected mode) apps. Thus, WINE on a 64-bit Linux will handle 64, 32, and 16-bit Windows apps, and there's no emulation unlike with DOSbox and such:
https://www.dkia.at/en/node/180
(Coincidentally, I recently made a comment on another article about the nuanced nature of the word "supported": https://news.ycombinator.com/item?id=19578503 )