Humans have been working it out for a million years or so, it isn't that difficult.
If someone considers relationships with other people to be an "incomprehensible minefield," then the problem is with them, not the nature of human relationships.
Too many people overthink things, seeing each potential relationship as a puzzle to be solved, or searching for some general purpose sexual algorithm for which they can provide the inputs and recieve sexual or emotional fulfillment, or they expect hostility and deception and treat dating like an interrogation.
And of course some people just don't have empathy for the opposite sex and don't understand social boundaries or cues.