The only hardline view on security you'll encounter in the wild is "security is practical in our computational environments"[1]. Only half-joking here.

My reading of Theo's quote is merely "the combination of x86/IA32/AMD64 and virtualization gives little to no factual security benefits, and plenty of pitfals".

I don't see Theo as being a hardliner about security, just meticulous about good engineering practices - as per OpenBSD's usual standards - and facing the problems & risks as they are.

[1] examples: "Rust/Java gives you security", "shortlisting the only allowed actions by end-user application gives you security", "hardcore firewalls give you security", "virtualization gives you security", "advanced architectures like Burroughs' give you security".