The Talos II I'm typing this reply on is just my regular workstation. I have a dual-4, which is 32 threads, and it runs Fedora. Most things work just fine and it's a very nice daily driver. I'll probably upgrade it to a dual-8 in the near future for even more parallel goodness.
I also have a Blackbird, which does streaming video in the home theatre and is also a test system. It's a single-4, but it can take an 8-core part if desired.