Ask HN: Packaging a Python application as a native windows/mac app

I have a python REST API built with Django and a React frontend. Right now the API is hosted on a bunch of Ec2 instances which works fine but I was hoping to make it work offline (people don't trust sending sensitive information to a third party server)

Ideally it would be something like jupyter notebook that launching the application, starts the web server then launches a browser tab that points to the launched web server. Has anyone done this before in a way that is frictionless for non-technical users?