Huh? Are you assuming large flat L2 networks addressed with IPv6?
IPv6 works great at scale, just route everything everywhere, stick with unicast & anycast, and don't roll large L2 domains. Multicast is entirely unnecessary aside from the small amount needed for ND/RA between host and ToR.
And, for operations, a routed IPv6 network without NAT, VXLAN, or VLANs spanned across switches is much easier to troubleshoot and generally has fewer moving parts to fail.