Yes, we see how angry they are when the extreme mistreatment of Syrian Sunnis or Chinese Uighur. Ah, wait, they even take part in the former. They do a fine job of making it appear the real issue is religious.
"For example, Iran was abiding by the JCPOA, as verified by IAEA inspectors,"
JCPOA and UNSC 2231 included far more than IAEA inspections, and Iran was NOT abiding by the other issues (ballistic missiles, heavy water, keeping a spare set of nuclear tubes for Arak, etc.).
People mostly repeat IAEA because they are unaware of the other issues, or that the deal had time limits on most inspection issues. Some are aware but prefer to elide it.
"The canard here is that Natanyahu was claiming Iran was trying to make nuclear weapons and that was unacceptable, despite the fact that Israel already has a well-known but never publicly acknowledged nuclear arsenal"
Israel isn't threatening to destroy Iran, it's the other way around.
"Even with nuclear weapons it is ridiculous to think that the Iranians do not understand the concept of Mutually Assured Destruction vis a vis Israel."
Some Iranian don't[0]. If you want to entrust the safety of the world to that, well...
[0] https://www.memri.org/reports/former-iranian-president-rafsa...