The "Wacom Desktop Center" app mostly just sits there looking for updates and bugging you to enable tracking anyway; the Mac version has a menu setting that
theoretically stops it from ever running, and thus bugging you to sign up to share your analytics. I just turned it off (since I just noticed it for the first time) but don't feel like rebooting to check if it actually works. (Though I did just run the little script I keep around to restart the driver, which normally brings up the WDC, and it did not show up this time. Huzzah!)
No idea about Windows, I never use that.