The advantage of Swift and SwiftUI is that my application can run on both a MacBook and iPad, sync data with iCloud.

The advantage of LispWorks is that I could fairly easily support both Mac and Windows (and Linux).

I spent two evenings last week playing with Clozure CL and its Cocoa support. It has low level APIs and I had a peculiar issue with sometimes not being enter text into input components.

EDIT: to be clear, in general I love Clozure CL. In this instance I was probably shooting myself in the foot, somehow, or maybe the issue was that I blew the install in some way getting it running on Catalina which took over an hour. The Catalina problems are hopefully just short term issues.