Rather, you want to dive as deep as possible, pick your battles very carefully, and get loot off the ground or from occasional fightable monsters. Hilariously, people have found that Ironman play (never leaving the dungeon, and always descending) is easier because it forces you to play like this.
When grinding, you will still run into out-of-depth monsters that will wreck you, so there is no way to play the game safe.