Want an easy concrete example? You and your cofounder have 10 years of Ruby experience and investors/customers who want a product yesterday. Or the deliverable that makes most sense is a PHP script that users can drag into CPanel because that's your customer base.
The tinkerer inside you always wants to try new things and convince you that some greener tech on the other side of the fence are going to make the difference. It's usually just procrastination from the actual hard stuff: building things people want, today.