You may have some luck with Wine or CrossOver. Unfortunately we don't currently test on macOS.
Edit: I've been told that the removal of 32-bit support in the latest OS versions makes macOS support unlikely. The game uses some old proprietary DLLs (for some file formats) that are 32-bit only. Sorry :(
Yes, of course. I think for a while we have been careful in maintaining compatibility with VMware's virtualization, though lately it is largely unnecessary (due to improvements in the VM software).