Emacs out of the box comes with a menu system. This is very good and useful for newcomers because it not only gives a familiar feel, it also helps discovering functionality. However, it is no coincidence that a lot of power-users turn off menu and toolbar, as evidenced e.g. by Steve Yegge's "effective emacs" tips (https://sites.google.com/site/steveyegge2/effective-emacs#it...). Now, not every user is a power-user, there is of course a spectrum, but to me it is fairly clear that the way Emacs is designed, mouse-based usage would be a limiting factor.