I feel like a
good touchpad (meaning Apple) is superior to most good mice for general desktop usage. What pushes touchpads clearly ahead is when you make good use of multi-touch gestures. Using third-party tools under macOS, about half of my most commonly used keyboard shortcuts can be replaced by gestures that are quicker and easier than reaching for the keyboard. The handful of apps with native multitouch and support for haptic feedback through the touchpad are also really nice.
I still use a mouse for gaming, but I have to replace it every ~3 years because the buttons start to wear out. That has yet to happen to one of my Apple touchpads.