I'd taken psychedelics perhaps 50-60 times before I had one out-of-nowhere bad experience that caused more harm than all the good I'd gotten out of them in my life.
I'm not against psychedelics after this either, huge supporter, but people like to pretend traumatic experiences don't have a chance of occuring.
I don't think I can do that much, but what I can do is offer some theories and context.
(Note: I wrote at length about this experience, and my general experiences with both psychedelics + MDMA here: https://news.ycombinator.com/item?id=22991744)
I'll write the following under the assumption that you/the reader don't have experience with psychedelics. There are some things you can put into words for those unfamiliar, and a great many other things you cannot.
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Psychedelics are a fundamentally neutral substance. What I mean by that is, that they and the experience, are neither good nor bad. As hippy as it sounds, "they are what you make of them".
This quality, if you ask me, boils down to one property: Psychedelics are enhancers. If you feel beautiful and happy and lively, you feel REALLY beautiful, happy, and lively.
If you start to become frightened/anxious of something, or are in a frightening situation, you become REALLY frightened.
And this becomes further amplified by a second property of psychedelics:
Rather than the usual business of "Some external occurrence or sensation happened, and here is my one thought/reaction to it." IE "Wow, that statement was rude, what a jerk." Or "Man, that dark alleyway looks kind of scary, I think I'll not go that way."
Your subconscious and free-association become stronger respective of dose, to the point where they can become runaway.
No longer is the equation "1 external action = 1 internal processing response", but some small experience can set off a chain reaction of internal association tumbling down a bunch of different paths.
Dark alleyway -> Oh that's scary -> That's the sort of place monsters would be -> Monsters, oh those are terrifying -> Murder is terrifying -> I don't want to be murdered -> There's probably a monster in that dark alleyway -> Dark alleyway, that's so terrifying -> You know what's probably in there, a monster? -> A monster would murder me -> I don't want to die -> Die.. death...
It becomes a looping, inescapable schizophrenic sort of experience where you've also lost enough short-term memory to forget you've been going in loops like this for what feels like years.
And because things are so ENHANCED, the amount of screaming terror, dread, etc you can feel is beyond any thing you can comprehend. Time is slowed to a crawl, this can continue for eternity.
Now, if that all sounds awful -- just imagine this whole scenario, but filled with the most intense happiness and love you can imagine. That's what MOST experiences are like, generally.
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What happened that night is I started getting anxious and fell into a dark place in my mind and got stuck there for an eternity instead of a happy place, to put it shortly.
I also won't pretend I probably didn't have a lot of subconscious trauma from a really messed up childhood and likely other mental issues/insecurities.
The time element of a deep LSD trip can make it very challenging. Being stuck in your thoughts for 18 hours is not for the light hearted
There are a significant number of people who view the psychedelic substances they use as teachers, as sacred, as emissaries of gods or other supernatural beings, or as those beings themselves.
Though such views are often dismissed as superstition or magical thinking by many who consider themselves part of "advanced", "civilized" societies, and who view these substances more as neutral tools, such societies' confrontation with these substances is relatively young, and I suspect that as they gain more experience with them their views will change.
Use of these substances have already been the wellspring from which multiple religions have come, and the potential for them to spawn more major religious movements, and with them a much more deferential attitude towards and view of these substances, will only grow as their use increases.
Kind of like how more experience with nature moved those same societies to not want to destroy it? While it's reasonable to question underlying prejudice and (frankly) very little actual knowledge I do not think that's going to be solved with more experience. We just don't see that reflected in reality. Most of Western society is fossilised, hostile and fundamentally exploitative. Having those attitudes change would involve a complete overhaul of the underlying cultures, which just isn't likely.