Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes (opens in new tab)

(journals.plos.org)

54 pointsInInteraction5y ago9 comments

9 comments

How do they net out the idea that people with healthy lifestyles would be less likely to have a vitamin D deficiency? (Better diet, more exposure to sunlight)

cameldrv5y ago

There was an actual randomized trial that came out recently [1] where hospitalized patients were given extremely large doses of Vitamin D (explanation of equvalent doses [2]) and it dramatically reduced ICU admission.

This supports the idea that Vitamin D helping with COVID is probably causal rather than just a correlation.

[1] https://www.sciencedirect.com/science/article/pii/S096007602...

[2] https://chrismasterjohnphd.com/covid-19/finally-confirmed-vi...

yokaze5y ago

One should not leave out the important part "pilot study". As said by the authors in the conclusions themselves, it still requires a larger one to give definite answer.

1 more reply

DarknessFalls5y ago

I would be interested to know if supplementation with Vitamin D + Vitamin K2 is more effective in improving survivability.

aplummer5y ago

They measure obesity and find it 0.02 vs 0.01 for vitamin d, which seems a decent enough proxy for lifestyle for this kind of study so your underlying point is valid here. Actually i think the biggest missing control is race.

I went in skeptical even though intuitively being deficient in vitamin d makes sense, this isn’t convincing but I agree with with their conclusion that it’s worth a bigger study.

If someone reading is wondering whether to maintain a healthy level of vitamin D to help if you get covid, yes you should. Should have done that before this study ofc.

thyrsus5y ago

Race can be a proxy for the amount of melatonin, which influences vitamin D. It can also be related to many other things. How would you use race to interpret the data?

1 more reply

techsin1015y ago

how much IU is this?

j / k navigate · click thread line to collapse

9 comments

tyingq5y ago

How do they net out the idea that people with healthy lifestyles would be less likely to have a vitamin D deficiency? (Better diet, more exposure to sunlight)

cameldrv5y ago

This supports the idea that Vitamin D helping with COVID is probably causal rather than just a correlation.

[1] https://www.sciencedirect.com/science/article/pii/S096007602...

[2] https://chrismasterjohnphd.com/covid-19/finally-confirmed-vi...

yokaze5y ago

One should not leave out the important part "pilot study". As said by the authors in the conclusions themselves, it still requires a larger one to give definite answer.

1 more reply

DarknessFalls5y ago

I would be interested to know if supplementation with Vitamin D + Vitamin K2 is more effective in improving survivability.

aplummer5y ago

I went in skeptical even though intuitively being deficient in vitamin d makes sense, this isn’t convincing but I agree with with their conclusion that it’s worth a bigger study.

If someone reading is wondering whether to maintain a healthy level of vitamin D to help if you get covid, yes you should. Should have done that before this study ofc.

thyrsus5y ago

Race can be a proxy for the amount of melatonin, which influences vitamin D. It can also be related to many other things. How would you use race to interpret the data?

1 more reply

techsin1015y ago

how much IU is this?

j / k navigate · click thread line to collapse