Yep. I know the device. While it's promising, e-ink has some inherent problems. Namely, color and speed.
I always design my software on paper first and, color is needed for diagrams. I also read academic papers a lot and use color-coded highlighters (remember / further research / etc.). Remarkable doesn't support these workflows.
e-ink is not a fast medium. I have an eBook reader (Kobo Glo HD / 300dpi) and I love it for reading but, highlighting process is slow and ugly (lower color depth -> overdrive for fast response -> repaint with correct gray levels -> done). Writing will be similar, with some lag and that's flow breaking and unacceptable for me.
At the end of the day, it's a good skeumorphic device which mimics paper albeit a rigid and slower one. On the other hand, paper's tactile response is unmatchable, especially when combined with fountain pens (which I use a lot).
Also, there are some ritualistic stuff with pen and paper. Every project has its own notebook, which triggers context response in my brain. When I get the notebook, I reload the stuff at the background. Every other task is automatically pushed back by the subconscious. It's a kind of leveraging the "library" system of the brain.
iPad pro has a faster screen and color but, backlit screens kill my eyes after a certain time period (All my panels are either OLED or high quality IPS with reduced blue light). I don't want to lose my eyesight for that.
I want to add that paper is hard to digitize, takes a lot of physical space and has maintenance but, these downsides are balanced out by the advantages it brings, at least for me.
I love working with digital systems. I use Pagico & Trello extensively. A digital diagram a lot. Keep structured knowledge bases in Evernote and Zim but, when it comes to thinking and documenting the thinking process, I always return to the pen & paper and, get that 10x boost instantly. I just can't replace it and I don't want to replace it anymore.
Trivia: Words like "On the other hand", "in that case", etc. comes from early memorization techniques where you imagine that you're actually putting that subject/idea in to your hand or a physical case which helps with structuring big subjects a lot. Using paper, different notebooks, etc. triggers the same circuitry to improve focus, retention and efficiency.