Yeah it is true, but the problem is if DoH with its privacy features come along it will be literally impossible to block ads with PiHole, as all DNS quesries will be encrypted (which DoH does ofc rihgt now).
So no ability to block ads in TV or malicious domains that IoT deviced connect to or even blocking Windows, macOS telemetry network wide as all DNS requests will be encrypted which they are not as of right now.
It will be possible, just harder. I will not be surprised if there will be services where one can get a database of IP addresses of bad domains and one could block that, the same way one does with spammers. Surely it may block sites that share hosting on those domains, but it then it puts pressure on sites to avoid such sharing sharing.