In theory, your software could run faster, or slower, depending upon Amazon's use of their extensions within their C library, or associated libraries in their software stack.
Maybe the wildest thing that I've heard is Fujitsu not implementing either 32-bit or Thumb on their new supercomputer. Is that a special case?
"But why doesn’t Apple document this and let us use these instructions directly? As mentioned earlier, this is something ARM Ltd. would like to avoid. If custom instructions are widely used it could fragment the ARM ecosystem."
https://medium.com/swlh/apples-m1-secret-coprocessor-6599492...