> delivery mechanism: you need to take a very unstable molecule, protect it from the environment - both external, and when inside the patient - and insert it into a human cell. (This is called the "platform", and is usually developed independently from the specific payload.)
Of note, the immune system is pretty good at destroying foreign mRNA so you also need to evade it.
This article is pretty good: https://berthub.eu/articles/posts/reverse-engineering-source...