There are too many examples of a forgotten offhand remark, a harmless off-color joke, or that one time you had a bad day and thought you were just venting to the handful of close friends who are the only people you think even know about your Twitter account coming back many years later to bite you in the ass when a future potential employer (or goodness forbid the media) decide to go spelunking in your personal social media and essentially treat that version of you from 11 years ago as the same person you are today.
Twitter makes it way too hard to mass delete old tweets or otherwise exercise fine control over whats on there.
With social media, the only way to win is not to play.