Not just in the region. In the 1970s, Israel worked with apartheid South Africa to develop nuclear weapons. South Africa has subsequently been disarmed, but Israel has not been.
Incidentally, in 1963 JFK was trying to stop Israel's nuclear weapons program because American intelligence had failed to turn up any evidence that other countries in the region were pursuing the same. In a letter to Ben-Gurion, JFK wrote:
> "I can well appreciate your concern for developments in the UAR. But I see no present or imminent nuclear threat to Israel from there. I am assured that our intelligence on this question is good and that the Egyptians do not presently have any installation comparable to Dimona, nor any facilities potentially capable of nuclear weapons production. But, of course, if you have information that would support a contrary conclusion, I should like to receive it from you through Ambassador Barbour. We have the capacity to check it."
Egypt never developed nuclear weapons.