Immuno-compromised people aren't some isolated hobbit species, they're people like you and me that have jobs, run errands, learn in schools, consume food, often live with other humans who have to go out in public, etc. And new folks with sub-par immune systems are born or created every day.
Many vaccine-resistant folks will throw this population away from the entire risk analysis equation, treating them as a mere error term. At least, this has been my observation. In my opinion they should just admit they don't care about the fate of others beyond the 'thoughts and prayers' passive level.
