Clearly Ibuprofen is a product of big pharma, therefore if it were merely distrust of big pharma then using it and all other ordinary drugs like it would be out of the question. Additionally, there are big lobby interests for products and services we all use all the time. Why make exceptions for them? Not trusting big pharma is post-facto rationalization as reasonable caution evaporated sometime before the first 500 million people got vaccinated. No, there are simpler underlying reasons like being disproportionately afraid of the vaccine vs the virus or not feeling any risk and not caring about the risk of others etc.