Developing targeted campaigns to encourage vaccination. There is hesitancy in the US black population, especially in the South, to trust health government-based health institutions. There's also less access to healthcare resources. See: Tuskegee Syphilis Study as a case
https://en.wikipedia.org/wiki/Tuskegee_Syphilis_StudyFor Latinos, there's a language gap that needs to be overcome for large projects like this (other notable example is census hesitancy due to risk of deportation for family and friends). Anything that can get you or your household on a government record garners suspicion from the recently immigrated and those housing undocumented people (even if the current government says it's OK, who's the say the next one won't raid your home?). The television pundits definitely don't help.
In my city, Cambridge, there was a huge vaccination push for the black population. It included priority access, more accessible clinics + hours, door-to-door advocacy/pamphlets, and getting support from local black institutions and community centers. Our rates for black residents shot up after that.
The deeper you read into the historical of medical abuse and misinformation towards minorities and the poor in the US, the faster you realize why targeting and messaging matters.