A computer is supposed to compute, but the RISC-V ISA does not provide everything that is needed for all the kinds of computations that exist.
The 2 most annoying missing features are the lack of support for multi-word operations, which are needed to compute with numbers larger than 64 bits, but also the lack of support for detecting overflow in the operations with standard-size integers.
If you either want larger integers or safe computations with normal integers, the number of RISC-V instructions needed for implementation is very large compared to any other ISA.
While there are people who do a lot of computations with large numbers, even the other users need such operations every day. Large number computations are needed at the establishment of any Internet connection, for the key exchange. For software developers, many compilers, e.g. gcc (which uses precisely libgmp), do computations with large numbers during compilation, for various kind of optimizations related to the handling of constants in the code, e.g. for sub-expression extraction or for operation complexity lowering.
So every time when some project is compiled, libgmp or other equivalent library for large numbers might be used, like also every time when you click on a new link in a browser.
So this case is not at all pathological, except in the vision of the RISC-V designers who omitted support for this case.
That was a good decision for an ISA intended only for teaching or for embedded computers, but it becomes a bad decision when someone wants to use RISC-V outside those domains, e.g. for general-purpose personal computers.
This is non-sense. You can still do everything you need. Its just that in some cases the code size is a bit bigger or smaller.
And the difference with compressed instruction is not nearly as big, if you add fusion the difference is marginal.
So really its not a pathological case its 'its slightly worse' case and even that is hard to prove in the real world given the other benefit RISC-V brings that compensate.
And we can find 'slightly worse case' in the opposite direction if we would go looking for them.
If you gave 2 equal skilled teams 100M and told them to make the best possible personal computer chip, I would bet on the RISC-V team winning 90 times out of a 100.