Thanks, Aaron. I think people who have been using Node for years are skilled at the old Node ways and have huge inertia in their skills, their own code, and others' Node code. For them, the ideal platform would be Node plus some upgrades. I'm guessing they would rather extend their inertial frame of reference than leave it behind.
Then there are others of us who have been saying no to Node and legacy JS for years. We have no such legacy to maintain and no intention of ever creating any. But some of us (at least I) would reconsider platforms built from scratch on a new TypeScript foundation rather than layered on a pre-ES6 foundation. That would include a Deno-based Electron. You might have more luck converting people who don't use Node than getting Node users to abandon their legacy.
The state of cross-platform desktop apps is terrible. All attention is on mobile, and desktop OS makers have almost zero interest in supporting cross-platform desktop apps. (MS cares a little more than zero, Apple less than zero and barely tolerates their own Mac-only developers.) Only something browser/Chromium based seems realistic for the next few years.
On the server, there are a lot of alternatives to Node that are considered better by (and very popular with) large segments of the market. Deno will be one of them, I think. But for cross-platform desktop apps, Electron would be rejected completely if the alternatives weren't so bad and unlikely to get better. A better Electron, despite its inherent problems, could end up more popular than server-side Deno. Just a thought.