Have sanctions ever worked for that? Iran has been under strict sanctions for years - they haven’t removed their regime, but the people there do burn American flags in the streets… Also in Cuba, Venezuela, North Korea it doesn’t seem to have helped… I don’t have any better ideas, just doesn’t seem like sanctions really work at all as either a deterrent or punishment…
I hate that innocent Russians are suffering from this and will suffer for years to come. But even if the sanctions won't help overthrow the regime, they will certainly make it harder for Russia to keep funding their war.
Russia is a modern country with quite a lot of wealthy people. Maybe this time they can put up enough pressure to change the leadership. Anyway this is all we can do without starting a world war